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J Exp Med (2018) 215(1):35775

After the washing step the R6G dye of the internalized non-targeted or targeted nanocarriers in living hECs was imaged using the 543 nm laser line on a Leica TCS SP5 confocal laser scanning microscope equipped with a sample holder kept at 37 C

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Restauration de la capacit des cellules immunitaires

The AMLS hypothesis postulates that in neuroinflammatory infectious diseases, such as TBM, lactate produced through glycolysis in astrocytes participates in the activated immune response and, in association with ketones and gluconeogenic amino acids, is collectively directed from the neurons preferentially into microglia