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These SMILES were then used as input for the tools SuperPred 59 and SwissTargetPrediction (STP) 60 to identify potential protein targets of the drugs

The co-sedimentation assay was performed as described previously 71

Tumors in the FeS@SRB-treated group were initially suppressed due to the Fenton reaction

Using a cytometry-based approach, we found that cells from cluster B (probably attributable to progenitors) showed most of the age-specific changes in H2AX signal (Extended Data Fig

The decreased sensitivity of cancer cells to these inhibitors may be due to several reasons, including extracellular GSH binding to and inactivating the inhibitors