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at high doses , it can become neurotoxic or act as a pro-oxidant

[7] [8] Intrinsic factor antibodies may be tested if pernicious anaemia is suspected

Although these are an essential part of responsible pet ownership (12), they add to the financial burden. Fortunately, posts demonstrate how owners are willing to spend more on their pets wellbeing

The MHRA recommends considering periodic B12 monitoring in patients on metformin who have risk factors for deficiency, and testing if symptoms develop

The result: stronger HbA1c reduction, weight neutrality or loss, and lower hypoglycemia risk often delaying the need for complex basal-bolus regimens