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Tirzepatide is the older, fully matured story: a single-molecule dual incretin agonist taken from discovery through Phase 1 proof-of-concept, [7] then through the large SURPASS (diabetes) and SURMOUNT (obesity) Phase 3 programs, and finally to FDA and EMA approval

The analysis integrates findings from preclinical investigations, limited clinical data, and regulatory perspectives

Topical and intraperitoneal addition of TB4 increased re-epithelialisation by 42% over saline controls at day 4, and by up to 61% at day 7 post-wounding