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Mechanistically, we show that, upon GSH depletion, the liver tissue induces the expression of target genes associated with the antioxidant transcription factor NRF2

In this study, a tocopherol mixture rich in gamma-tocopherol that was incorporated into the diet reduced tumor growth up to 80% in mice after 50 days of treatment

In contrast, the ZVAD co-treatment failed to suppress the uptake of PI in RSL3-treated 3D PTC spheroids, mirroring tumor cell viability findings in 2D

Glutathione supplementation suppresses muscle fatigue induced by prolonged exercise via improved aerobic metabolism 20