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Vuong B, Odero G, Rozbacher S, Stevenson M, Kereliuk SM, Pereira TJ, et al

The pattern repeats

Int Immunopharmacol 47:95105

Several lines of evidence show that ApoE4-mediated astrocytic protein changes have a multitude of damaging effects that include reduced spine density and shorter spine length (Nwabuisi-Heath et al., 2014), increased tau-mediated synaptic loss (Wang et al., 2021), reduced expression of postsynaptic density protein 95 (PSD-95, also known as synapse-associated protein 90