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Previous studies have shown that SFN has antioxidant, antineoplastic, antiangiogenic, anti-inflammatory, and antibacterial properties [13, 34]

Because such rapid activation of effector functions is associated with substantial metabolic demands, a critical aspect of neutrophil metabolism is to understand how they utilize limited metabolic resources to support the considerable increase in metabolic demand within a short time

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Furthermore, diastolic function worsens with age, likely due to increased stiffness of myocardium while the LV systolic function remains intact at rest (Upadhya and Kitzman, 2017)