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Association between osteonecrosis of the jaws and chronic high-dosage intravenous bisphosphonates therapy

L.AntelmannH.ParsonageD.UptonH.RawatM.et al

Cell Metab 2019;29:156-73.e10

doi: 10.1074/jbc.C000405200

In this regard, Numata et al., (2012) has proved the role of epigenetics in cortical development across the lifespan by examining the prefrontal cortex in a genome-wide study of DNA methylation in ~14,500 genes at ~27,000 CpG loci focused on 50 promoter regions in post-mortem samples from 108 individuals aged from 14 weeks of gestation to 83 years [8]