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End-stage tumors showed alterations in a host of lipids and metabolites associated with oxidative stress and aerobic/anaerobic respiration

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The fact that cancer cells can use glutaminederived carbons to fuel the TCA cycle, or use glucosederived carbons to both replenish the TCA cycle and synthesize glutamine may reflect a certain degree of metabolic plasticity of tumor cells, aimed at optimizing their growth in shifting nutrient conditions

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Build In Some Wind-Down Time In the hour before you go to bed, wind down by dimming lights, turning off screens, and trying a warm bath or mindfulness exercises