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Primary bronchial epithelial cells, collection, storage, and use of tissue were performed in agreement with the Code for Proper Secondary Use of Human Tissue in the Netherlands ( The scientific board of the MPTC approved the use of materials for the present study under MPTC2010-019

The combination covers both short-term recovery and long-term renewal

However, the inevitable tissue disruption on extraction into aqueous buffer has the potential to generate artifacts arising from the interaction between a GST and a ligand usually found in a different compartment, or the generation of ligands formed through chemical- or enzyme-mediated oxidation during extraction

For instance, in certain scenarios, the absence of p53 suppresses the nuclear accumulation of dipeptidyl peptidase-4 (DPP4), fosters the formation of DPP4 and NOX1 complexes, and thereby intensifies lipid peroxidation, leading to ferroptosis [65]

It has been studied for its effects on endurance, recovery, cardiovascular health, and cognitive function