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DiY has been suggested to contribute to spores resistance to lytic enzymes (Briza et al., 1990) and has been suggested to be involved in the biosynthesis of thyroxine and melanin (Bayse et al., 1972)

RTEL depletion increases G4 stability at telomeres to prevent telomere replication (Uringa et al., 2012)

Molecular oxygen (O 2 ) can unpair and leave free radicals which are highly unstable and reactive, leading to the formation of ROS [45, 46]

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Even though this review has shed more light on the role of different brain cell types in ferroptosis during AD, whether ferroptosis in glia cells is related to later stages of the pathology should be investigated further