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This reflects findings made in PD patients, thereby demonstrating a higher immune-related face validity of the AAV1/2-A53T-SYN mouse model compared to the toxin-induced MPTP and 6-OHDA models

If these mutations occur in critical cancer-associated genes, they can lead to unchecked cell proliferation and malignancy

Over time, the body naturally removes these pigment deposits, making this process effective for tanning and pigmentation

radicals depend on the local environment with numerous possible reaction pathways, including tryptophan oxidation to kynurenine 39 , L- to D-isomerisation 40 and backbone cleavage 12