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The term "treatment and/or prevention", as used herein, means administration of a fingolimod, an analogue, metabolite or derivative thereof or a pharmaceutically acceptable salt thereof, or a pharmaceutical formulation comprising fingolimod, an analogue, metabolite or derivative thereof or a pharmaceutically acceptable salt thereof, to preserve health in a patient suffering or in risk of suffering an adrenoleukodystrophy, preferably adult adrenomyeloneuropathy (AMN), cerebral adrenomyeloneuropathy (cAMN) or the childhood variant of adrenoleukodystrophy (cALD) adrenoleukodystrophy, even more preferably adrenomyeloneuropathy (AMN)

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The risk factors of NEC include premature delivery, no breastfeeding (151), increased antibiotic exposure (152), and intestinal microbial ecological imbalance (153)