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(2000) Mixed disulde with glutathione as an intermediate in the reaction catalyzed by Heavy metal resistance Herbicide resistance Precursor of S compounds ROS metabolism GR GRX DHAR Metabolite synthesis Light signalling Redox signalling Detoxification Pathogen defence GSH GSSG GRXs Regulation of S metabolism Phytohormone Cell division and meristem function Flower development Phytohormone pathways Transport Figure 9

Most in vivo studies remain short-term and small-scale, offering limited insight into the chronic oxidative and inflammatory complexity of human wounds

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Furthermore, we investigated the metabolic fate of U- 15 N glutamine in vivo by LCMS, which produces glutathione containing one 15 N atom via GSH de novo synthesis (Fig