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It has a wide spectrum of metabolic effects, including induction of apoptosis via ROS production and cytochrome c release (17), inhibition of NADH oxidation (18), and loss of GSH (19)

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Since decreased Parasutterella relative abundance may accompany increased stress 80,81 , the increased Parasutterella relative abundance that occurred in this study following diet switch likely arose from the weight loss-mediated negative energy state

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