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However, it should be noted that the response of GPX4 inhibitors in different cancer cell lines is not consistent (Zou et al., 2019)

Regulation of other signaling pathways In addition to Nrf2 and insulin signaling pathways, lipoic acid was found to target other cell-signaling molecules thereby affecting a variety of cellular processes, including metabolism, stress responses, proliferation, and survival

Phosphorylated CXCR4 is associated with poor survival in adults with B-acute lymphoblastic leukemia

Nutritional supplements, such as fiber supplements, bioactive compounds, and fermented foods also regulate gut microbiota [165]