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This would mean comparing their impacts on SLE-specific immunological biomarkers such as autoantibodies titers, complement proteins (C3, C4), cytokines such as IL-6, IL-10, and TNF-, and T cell subsets (especially the Th17/Treg ratio), to assess efficacy and monitor disease progression, and clinical manifestations

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J Neurochem 93:611623

aureus to bind to the Fc at a site that overlaps with that of FcRn and the Fc:Fc contacts needed for efficient complement activation 45