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On the other hand, clinical trials also carried out to investigate the combination therapy of glutamine inhibitor CB-839 and other anticancer drugs

Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2

elegans model of PD with RNAi-mediated bcat -1 knockdown, metformin reduced mitochondrial respiration, rescued neuronal viability, and significantly improved motor function, possibly through inhibiting complex I [156]