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Description

Maehara, Miki, et al

Key Takeaways Cyanocobalamin is a synthetic form of vitamin B12 used in supplements and therapies

Cobalamin deficiency can cause a host of symptoms, including: Tiredness and weakness Nausea Decrease in appetite/weight loss Poor memory and concentration Sore mouth/tongue Numbness/tingling in limbs Vision problems and balance issues Heart palpitations Depression and irritability

Complementary work has documented activation of the VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) pathway, involved in angiogenesis, along with upregulation of early growth response genes (Egr-1) and the FAK-paxillin transcription factor in studied endothelial cells