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Buttock/leg (sciatic distribution, lumbosacral dermatomes): pain down the buttock and back of the leg, sometimes with numbness in the foot

an overview of preclinical and clinical studies performed can be found in Table 1 and Table 2, respectively

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Despite the absence of codified guidelines, BTX-A has been applied from the early 1990s for the treatment of asymmetries caused by FNP, with promising results and improvements in quality of life [10]

By engaging all three pathways, researchers aim to observe more comprehensive metabolic regulation than is possible with single-receptor agonists