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Used primarily to treat high blood pressure (hypertension) and heart failure, it belongs to a class of drugs known as angiotensin-converting enzyme (ACE) inhibitors

The combination is substantially superior to either componentdemonstrating true complementary mechanism-based additive effects rather than simple additivity

10.1038/s41577-019-0178-8 116 TsukimuraN.YamadaM.AitaH.HoriN.YoshinoF.Chang-Il LeeM.et al (2009)

While chickenpox is characterized by an itchy rash that can occur anywhere on the body, shingles typically has a more limited distribution, often appearing on one side of the body or face in a band-like pattern following the path of a nerve