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This work was supported by the National Natural Science Foundation of China (21822605, 22022603, and 21677068), the Fundamental Research Funds for the Central Universities (021114380148), Chinese Public Science and Technology Research Funds for Ocean Projects (201505034), and the program B for Outstanding Ph.D

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"Stress signalling pathways that impair prefrontal cortex structure and function." Nature Reviews Neuroscience, 2009 (PMC2907136)

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The animals were treated daily during five weeks with L-NAME (10 mg/kg b.w.), L-arginine (100 mg/kg b.w.), NaBPC157 (10 g/kg b.w.) and their combinations (L-NAME + NaBPC157, L-NAME + L-arginine) intraperitoneally

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Participants were randomly assigned (1:1) to receive either escitalopram (ESC, n = 9

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