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Additional studies are needed to elucidate these findings

In the future, the regulatory field around peptides may partly mirror the regulation of dietary supplements: they are regulated, but their safety must be supported by evidence of no harm, and promises about outcomes must be realistic and tightly tied to available data

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In addition, TNF- induces the expression of PDK1 via PI3K/Akt-HIF-1 in bFLS 24 and thus might interfere with pyruvate mitochondrial utilization through the TCA cycle 53