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Seven percent and above enters territory where the MMP balance concerns become more relevant

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[3] At the 12 mg dose, the mean weight reduction was about 17.5% at 24 weeks (the primary endpoint) rising to roughly 24.2% at 48 weeks , compared with about 2.1% for placebo

Theres a rationale behind localized injection: some practitioners use it near a specific treatment area on the theory that proximity might concentrate effects locally

That makes cagrilintide less of a direct competitor and more of a potential alternative for people whose bodies dont respond well to GLP-1 therapy, or who struggle with its side effects