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11 The fluid itself is viscous when injected and it is thought that viscosupplementation temporarily restores the viscoelastic properties and therefore the lubricating and shock-absorbing effects of the synovial fluid

Of approximately 4,000 affected genes, 59% are upregulated while 41% are downregulated, generally shifting expression patterns from diseased toward healthier states

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Given that the global IBS prevalence is approximately 4% under Rome IV criteria, the post-COVID increase represents a substantial disease burden

Both may stimulate collagen, but work through different mechanisms