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Wilson MP, Plecko B, Mills PB, Clayton PT

However, it cannot completely prevent natural greying caused by ageing or genetics

however, smoking cessation usually leads to weight gain, often substantial [18, 19], and could therefore differentially affect body weight if participants decided to stop smoking during the trial [19,20,21]

The primary glucose-lowering effect of metformin resides in the gut, not the circulation: results from short-term pharmacokinetic and 12-week dose-ranging studies

7.2.1 Non-monotonic dose-response relationships 7.2.1.1 Mechanistic understanding of NMDR effects Many EEDs exhibit non-monotonic dose-response curves where low-dose exposure produces greater biological effects than high-dose exposure (139)