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[142] However, patients with severe renal dysfunction may have altered drug distribution or concurrent conditions that could affect ondansetron pharmacokinetics

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It also suppresses the oxidation of low-density lipoprotein, quenches hydroxyl and other reactive oxygen species, and chelates iron in a manner that blocks iron-driven lipid peroxidation

Upon intravenous administration, the S/Ce-PABMS displayed maximal concentration within dopaminergic neurons at 12 h post-injection, demonstrating effective brain targeting (Fig