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Senolytics, drugs that eliminate senescent cells, show great potential in oncology, offering the possibility of selectively targeting cancer cells that enter a state of senescence without affecting healthy cells

Scientific Reports, 10 (1), 1-11

Design, synthesis and structure-activity relationship (SAR) studies of an unusual class of non-cationic fatty amine-tripeptide conjugates as novel synthetic antimicrobial agents

The keloid tissues for organ culture were firstly incubated in a DMEM containing 10% FBS at 37 C for 24 h, and the medium was replaced by the DMEM containing 2% FBS, the final concentration of 25 M FOXO4-DRI was added in the medium immediately