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A 2015 study published in the Annals of Clinical and Laboratory Science found that intra-articular (injected into the joint) AOD-9604 enhanced cartilage regeneration in a rabbit model of knee osteoarthritis

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However, chronic GH treatment carries substantial risks, including glucose intolerance, insulin resistance, diabetes, cancer, and cardiovascular complications

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The difference between clinical and practical dosing Clinical trials operated under controlled conditions that do not reflect real-world use