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It could have been one, one, one

Zilu et al

Global health estimates 2016: deaths by cause, age, sex, by country and by region, 20002016

10.1007/s00213-006-0417-0 215

BKM120 combined with cetuximab and irradiation significantly inhibited orthotopic xenograft tumors of HNSCC, which provided a rationale for clinical treatment