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Furthermore, combining network pharmacology with metabolomics allows for more robust verification of the multi-target mechanisms underlying Chinese medicines antidepressant properties, thus strengthening the scientific foundation for its clinical application [548]

Depletion of microglia and inhibition of exosome synthesis halt tau propagation

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We discuss how ME/CFS emerges from an intricate web of genetic vulnerabilities and environmental triggers, notably viral infections, leading to a complex series of pathological responses including immune dysregulation, chronic inflammation, gut dysbiosis, and metabolic disturbances