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One important consideration for kidney stone formers is often overlooked: people who have a history of kidney stones may be more susceptible to chronic kidney disease

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Moreover, substances such as statins, angiotensin-converting enzyme inhibitors, or AT1-receptor blockers, which possess indirect antioxidant properties mediated by the stimulation of NO production and by the simultaneous inhibition of superoxide production, have been shown to improve vascular function in pre-clinical and clinical studies and to reduce the incidence of cardiovascular events in patients with cardiovascular disease (Mnzel et al., 2010)