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In the landmark SURMOUNT-1 trial, participants receiving the highest dose of tirzepatide lost an average of 22.5% of their body weight over 72 weeks, making it one of the most effective pharmaceutical weight loss interventions available (Jastreboff et al., 2022, New England Journal of Medicine )

Biochemical and pharmacological interactions between nitroglycerin and thiols

Within the OL population, distinct subtypes were identified: OPCs expressing Pdgfr , Vcan , and Cspg4

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