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Policy and governance gaps include fragmented state-level legislation, weak institutional coordination, insufficient funding, and low-cost recovery, particularly in agriculture, where farmers cannot afford treated wastewater 147,148

In support, a 2004 clinical trial by Karl Mann reported a 36.1% abstinence rate with acamprosate, compared to 23.4% with placebo, stating its role in relapse prevention when combined with behavioral therapy

Moreover, the utilization of sophisticated instruments, such as digital intraoral scanners, is intended to enhance the precision and reproducibility of measurements, thereby strengthening the methodological rigor