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People with dietary B12 deficiencies are often given daily injections of 30 mcg for 5-10 days, with monthly maintenance doses of 100 to 200 mcg

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Cycling is about three real things: unknown long-term human safety, a systemic methylation effect the literature admits it hasnt fully characterized, and the genuine possibility of compensatory pathways routing around sustained inhibition

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Although it has ben studied in Phase I and II trials, these studies did not lead to an approval, likely due to its unclear risk-benefit profile