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This protective effect was mediated by the upregulation of Nrf2 mRNA expression, which alleviated oxidative stress (restoring GSH and GPX levels) and inflammatory responses (reflected in reduced TNF- and IL-6 levels) [99]

In a randomized controlled trial, the addition of oral vitamin C (500 mg per day) to bismuth quadruple therapy was compared with the same quadruple therapy alone

The trajectory of Tesofensine research highlights the dynamic nature of drug development and the potential for medications to find new therapeutic applications as our understanding of their mechanisms and effects evolves

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