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Study participants whose diets contained the lowest amounts of foods containing natural lutein and zeaxanthin experienced the greatest AMD risk reduction from taking the daily nutritional supplement

5A and Supplementary Fig

copri is enriched in human OA patients yet beneficial in mouse modelsurgently requires intensive investigation in multiple aspects, such as strain-specific differences (e.g., metabolic function distinctions between pathogenic and beneficial strains), dynamic regulation of the host immune microenvironment (e.g., the effect of inflammatory status on the microbiotahost interaction), and the effect of environment in influencing the effects of metabolites (for example, the effect of regulation of gut niches and availability of nutrient substrate for the production of bioactive entities such as paraxanthine)

LUV preparation A lipid mixture was prepared in a glass vial using the lipid composition shown in Supplementary Table 1

It guides decisions about when to start treatment and which options are realistic