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Description

The most common causes include B12 supplementation (particularly injections), liver disease releasing stored B12, haematological disorders increasing B12-binding proteins, and chronic kidney disease reducing B12 excretion

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The injection was the routine administration of the Tdap vaccine in his school, with parental consent

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Preclinical studies demonstrate elevated intracellular NAD+ levels following NNMT inhibition, suggesting a role in metabolic energy regulation

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The pathomechanism is still unknown

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Roth, M., Wang, Z

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