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Nanocarrier drugs have been identified as an ideal targeted therapeutic strategy for cerebral ischemia, with the ability to efficiently deliver drugs to the damaged brain parenchyma and further to specific cells, such as neurons or glial cells, with an increased chance of drug targeting due to the longer circulation time required for nanodrug delivery (Li et al., 2021)

Placebo preparation Placebos are an important methodological tool, used in research studies testing drugs in vitro and in vivo

In addition, KD reduces the release of mitochondrial cytochrome c, thus achieving a neuroprotective effect (136)

research is supported by funding from ZJU 100 Young Professor Project, Rut and Arvid Wolff Memorial Foundation (2023-02467), ke Wiberg Foundation (M19-0266), Fredrik and Ingrid Thuring Foundation (2019-00488)

"The incidence of infusion reactions associated with monoclonal antibody drugs targeting the epidermal growth factor receptor in metastatic colorectal cancer patients: A systematic literature review and meta-analysis of patient and study characteristics"