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The most consistent biochemical abnormalities seen in late onset LAL-D include elevated liver transaminases and plasma lipids

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Looking at the ratio alone can highlight risk, but combining it with related tests helps identify the underlying cause

Acta Pharm Sin (2015) 5(5):37889

Oxidative stress can promote the production of inflammatory cytokines, and free radicals can react with protein, lipids, nucleic acids and other cellular macromolecules, playing an important role in the pathogenesis of RA (197)