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doi: 10.1038/s41467-020-19793-8 48

Some researchers notice nothing significant initially

A negative feedback mechanism involving the hypothalamus, pituitary gland, and thyroid gland regulates thyroid hormones secretion as follows: The hypothalamus secretes TRH (thyrotropin-releasing hormone), which stimulates TSH (thyroid-stimulating hormone) release from the pituitary gland

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