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If suspicion of a CMCD is high (clonality prediction score 2), the criterion standard for diagnosing SM or MMAS is a bone marrow biopsy, which should ideally be performed in a center with expertise in SM since the burden of abnormal mast cells is typically quite low in those patients [49, 55, 65]

SERMs are non-steroidal estradiol analogs with mixed agonist-antagonist effects on ERs and are used in osteoporosis and breast cancer treatment (Jordan, 2004)

The Context First lets set the scene of why and how medicines are classified in the UK and the circumstances in which a change might be made

Endotoxin-free materials help researchers interpret laboratory results with fewer contamination-related variables