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Inhibition of glutathione-S-transferase as a treatment strategy for multidrug resistance in childhood rhabdomyosarcoma

In mammalian cells, FAM134B carries an LC3 interaction region (LIR), which specifically recognizes the LC3/GABARAP family, and an ER homology domain (RHD), which is involved in fragmenting the ER into small segments, enabling engulfment by the autophagosome [32]

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Epub 2017 Aug 30

This observation is the conceptual anchor of an entire branch of supplementation research the research into glutathione precursors, NAC, and the cysteine pool