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Description

The CD4 + T-cell-specific deletion of ASCT2 significantly suppressed the immune response of Th1 and Th17 cells in a mouse EAE model (81)

Human trials are small, but results have been promising

This index was significantly lower, not exceeding 30%, in the case of monotherapy, except for the OV1946 cell line, where the percentage was approximately 60% for ABT-263 and about 50% for olaparib [137]