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Br J Sports Med 39:767775 Chang C, Tsai W, Hsu Y, Pang J (2014) Pentadecapeptide BPC 157 enhances the growth hormone receptor expression in tendon fibroblasts

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In addition, MAPKs, as the central mediators that transmit extracellular signals from cell membrane to nucleus, can regulate the activation of Nrf2 and NF-B pathways to reduce cell injuries (Pan et al., 2018)

Wang and colleagues demonstrate that HG in the form of hydrogen-rich saline inhibits the activation of NF-B, thereby reducing pro-inflammatory cytokines [33]