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Retrieved 2024-01-25

They do not constitute medical advice, diagnosis, or treatment

Increased Nausea and Gastrointestinal Side Effects Nausea is one of the most common side effects of tirzepatide, affecting up to 25% of patients in early dose escalation

Conversely, 20-HETE, the primary HETE metabolite in the CYP450 pathway, has been implicated in impairing insulin and glucose homeostasis

Some patients notice brief injection-site soreness, and anyone with a B12 or vitamin sensitivity should talk through the formula with their provider before starting