l carnitine cardiomyopathy Role of L-carnitine in Cardiovascular Health: Literature Review Carnitine Deficiency - an overview

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Flavonoids can be summarized to reverse MDR via multiple mechanisms such as regulating the ABC transporters, boosting ROS production in cancer cells, or conversely inhibiting the activities of the anti-oxidative enzymes, subduing the proliferation of cancer stem cells, inhibiting EMT (epithelialmesenchymal transition) signalling, modulating autophagy and the related factors, and lastly, by distorting the progression of cell cycle in cancer cells [202]

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Come accennato, infatti, grazie al suo meccanismo d'azione, la carnitina in grado di prevenire l'accumulo dei gruppi acetile e dei gruppi acilici all'interno del mitocondrio che si generano in seguito ai processi di beta-ossidazione degli acidi grassi