Class Propionic acid derivative NSAID Mechanism of Action Reversibly inhibits COX-1 and COX-2 Prostaglandin synthesis pain, inflammation, fever Indications Mild to moderate pain (headache, dental pain) Dysmenorrhea Musculoskeletal pain Fever Osteoarthritis & rheumatoid arthritis Acute inflammatory conditions Dosage Adults 200400 mg every 68 hours Maximum: OTC: 1,200 mg/day Prescription: 3,200 mg/day Children 10 mg/kg per dose every 68 hours (max 40 mg/kg/day) Adverse Effects Gastrointestinal Gastritis Peptic ulcer disease GI bleeding Renal Acute kidney injury Sodium & water retention Cardiovascular Blood pressure Thrombotic risk (less than COX-2 selective NSAIDs) Others Hypersensitivity reactions Bronchospasm (aspirin-sensitive asthma) Contraindications Active peptic ulcer disease Severe renal impairment NSAID hypersensitivity 3rd trimester of pregnancy Uncontrolled heart failure Drug Interactions Anticoagulants bleeding risk ACE inhibitors / diuretics renal function Other NSAIDs toxicity Take with food to reduce GI irritation Avoid chronic use in elderly Safer than aspirin for GI bleeding, but not risk-free Avoid dehydration while using Ibuprofen = reversible COX inhibitor with good anti-inflammatory effect To view or add a comment, sign in PROTON PUMP INHIBITORS (PPIs) Definition: PPIs are drugs that irreversibly inhibit the H/K ATPase (proton pump) in gastric parietal cells, leading to suppression of gastric acid secretion
Incorporating a soothing serum or treatment that contains ingredients like aloe vera or chamomile can provide additional relief
A prescription must be written and dispensed by a pharmacist, which takes time remember that if you have any doubts, you have the right to change your mind and withdraw from undergoing the treatment Vitamin B injections can help support people who may not get enough B vitamins from other sources, such as those who are pregnant, vegan, or have certain medical conditions that prevent vitamin B12 from being absorbed
Inter-observer variation in laparoscopic findings is substantial, particularly for subtle or atypical lesions
Some Limitations While our results should hold true on top of other GOLDEN Paints, Grounds, Gels, and Mediums, because there are so many variables and combinations, it is always important to test for your application
