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Non-Alcoholic Fatty Liver Disease Non-alcoholic fatty liver disease (NAFLD) is a condition characterized by hepatic steatosis, which may progress to non-alcoholic steatohepatitis (NASH) with more severe liver damage [125]

Disclosure of interest: All author have nothing to disclose

Norrenberg M

As was pointed out, there is no toxicity without protein binding but there can be protein binding without toxicity [39]

Wnt/-catenin signalling pathway The Wnt/-catenin signaling system is extremely conserved, with important regulatory functions in cell stem cell development, differentiation, proliferation, migration, and apoptosis