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People with Pernicious Anemia: This autoimmune condition prevents the absorption of B12 in the digestive tract, making injections the most effective treatment

While ZO-1, occludin and claudin-1 expression was reduced, expression of paracellular cation- and water- channel-forming claudins 2 and 15 was increased

In Parkinson's disease, oxidative stress plays a role in damaging the neurons that produce dopamine, a crucial brain chemical

Tumor Necrosis Factor-alpha (TNF-alpha) Enhances miR-155-Mediated Endothelial Senescence by Targeting Sirtuin1 (SIRT1)

Deficiency of 5-methyladenosine phosphorylase (MTAP), a key enzyme in polyamine metabolism in tumors, can accelerate the accumulation of 5-deoxy-5methylthioadenosine (MTA) in the TME, ultimately reducing the maturation of dendritic cells and the activation of T cells